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10-Day Road Trip to Italy: Rome to Milano Highlights Through Florence, Pisa, Portofino

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This 10-day Italy road trip from Rome to Milan is perfect for culture lovers, nature enthusiasts, and families alike. Journey through iconic historical landmarks like the Colosseum, Vatican Museums, and Duomo di Milano, while also exploring picturesque lakes such as Lago di Tovel and Lake Como. Enjoy scenic mountain vistas with stops at Seceda and Alpe di Siusi, and unwind at charming coastal towns like Portofino and Sirmione. The itinerary blends cultural highlights, outdoor adventures, and leisure experiences, making it ideal for travelers seeking a comprehensive taste of Italy’s rich heritage and natural beauty.

Suitable Period :

Spring (March to May)
Summer (June to August)
Fall (September to November)

Trip Type :

Car Road Trip Itinerary

Estimated Trip Cost (Activities Only) :

245$ - 258$

*Per One Adult Person (Estimate)

*Prices may change

Car Rental

Day 1: Rome

Arrival day exploring iconic landmarks in central Rome

Total estimated duration of visits to places for this day: 6h 59m